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 Southern Medical Journal

Southern Medical Journal The Southern Medical Journal articles span the spectrum of medical topics, providing timely, up-to-the-minute information for primary care physicians and specialists alike. Contributors include leaders in the health care field from across the country...

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  • Knowledge, Attitudes, and Use of Emergency Contraception Among Hispanic Women of North Carolina. -
    Almost half of the 213 Hispanic women of the western North Carolina surveyed reported knowing about emergency contraception (EC) even if not by that name, and 12% reported use. Few (15%) had a moral objection to EC. Almost all said they would seek accurate information from their provider or health clinic, but only 21% reported discussing EC with a care provider. Of the 63 potential candidates for EC, 70% reported inconsistent use of birth control, 21% reported previous use of EC and 44% reported a willingness to use EC in the future.
    Page: 17
    DOI: 10.1097/SMJ.0b013e318187e7aa
    Authors: Galvin, Shelley L. MA; Fagan, E Blake MD

  • Warning Signs and Symptoms of Subarachnoid Hemorrhage. -
    Despite recent advances in neurosurgical techniques, the overall outcome following an aneurysmal subarachnoid hemorrhage remains poor. Knowing the possible risk factors and warning symptoms responsible for the event can lead to an earlier diagnosis and as a result, prevent subsequent complications.
    Page: 21
    DOI: 10.1097/SMJ.0b013e318188383c
    Authors: Togha, Mansooreh MD; Sahraian, Mohammad Ali MD; Khorram, Majid MD; Khashayar, Patricia MD

  • Prevalence of Intra-abdominal Surgery: What Is an Individual's Lifetime Risk? -
    This is a retrospective study using autopsy data to establish the prevalence and lifetime risk of intra-abdominal surgery. Over an 8-year period, 2,648 autopsy and clinical records from a public and private hospital were reviewed for evidence of intra-abdominal surgery. The lifetime risk of intra-abdominal surgery can be used to assess the utilization of health care among ethnic groups and in considering the role of incidental surgery.
    Page: 25
    DOI: 10.1097/SMJ.0b013e318182575b
    Authors: Nunoo-Mensah, Joseph William BMBS, FRCS (Eng); Rosen, Michael MD; Chan, Linday S. PhD; Wasserberg, Nir MD; Beart, Robert W. MD

  • The Effects of Body Fat Distribution on Pulmonary Function Tests in the Overweight and Obese. -
    Body weight is known to have an important effect on pulmonary functions. A number of studies have reported an inverse relation between respiratory function and various indices of obesity or fat distribution. Our findings are of clinical importance as they indicate that respiratory functions are affected even in mildly and moderately obese cases.
    Page: 30
    DOI: 10.1097/SMJ.0b013e31818c9585
    Authors: Ceylan, Emel MD; Comlekci, Abdurrahman MD; Akkoclu, Atila MD; Ceylan, Cengiz MD; Itil, Oya MD; Ergor, Gul MD; Yesil, Sena MD

  • Hantavirus Pulmonary Syndrome in Texas: 1993-2006. -
    A review of 28 cases of hantavirus pulmonary syndrome (HPS) reported to the Texas Department of State Health Services from 1993 through 2006 is presented.
    Page: 36
    DOI: 10.1097/SMJ.0b013e318187d06f
    Authors: Rivers, Megan N. BS; Alexander, James L. DVM, MPVM; Rohde, Rodney E. MS; Pierce, J Rush Jr MD, MPH


  • The Role of Observation in the Management of Atypical Nevi. -
    The question of whether or not partially removed atypical nevi should be re-excised with clear margins in order to prevent their evolution into melanoma remains unanswered. Although studies have shown that most atypical nevi will never progress into melanoma, re-excision, when biopsy margins are positive, is commonly practiced. We argue that re-excision in such cases is not necessary. The results of our study support observation as a safe alternative to re-excision for incompletely removed atypical nevi.
    Page: 45
    DOI: 10.1097/SMJ.0b013e3181904289
    Authors: Kmetz, Emily C. MD; Sanders, Holly MD; Fisher, Galen MD; Lang, Pearon G. MD; Maize, John C. Sr MD




  • Peritoneal Tuberculosis: Modern Peril for an Ancient Disease. -
    Extrapulmonary manifestations of Mycobacterium tuberculosis (MTB) in general, and tuberculous peritonitis (TBP) in particular, have posed complex diagnostic challenges for centuries. As the incidence of tuberculosis is declining in developed nations, clinicians may overlook the need to establish an early diagnosis and prompt therapy for this disorder.
    Page: 57
    DOI: 10.1097/SMJ.0b013e31819007c8
    Authors: Kosseifi, Semaan MD; Hoskere, Giendra MD; Roy, Thomas M. MD; Byrd, Ryland P. Jr MD; Mehta, Jay MD

  • Importance of Postprandial Glucose Levels as a Target for Glycemic Control in Type 2 Diabetes. -
    Postprandial hyperglycemia is nearly universal in patients with uncontrolled diabetes, it is common in well-controlled patients, and it is associated with poor outcomes. The goal of this manuscript is to highlight the importance of postprandial glucose levels in diabetes management by describing the pathophysiology of postprandial hyperglycemia, the consequences of elevated postprandial glucose (PPG), the therapeutic interventions for controlling PPG, and the impact of agents targeting PPG on cardiovascular outcomes.
    Page: 60
    DOI: 10.1097/SMJ.0b013e318188898e
    Authors: Tibaldi, Joseph MD

  • Consequences of Delaying Progression to Optimal Therapy in Patients with Type 2 Diabetes Not Achieving Glycemic Goals. -
    Insulin is the most efficacious therapy for diabetes, but its introduction to treatment regimens is often delayed. This delay results in worsened glycemic control, compromising the patient's long-term prognosis as a consequence of an increased propensity for complications. Earlier initiation of insulin can help minimize or even avoid these complications, and modern formulations and delivery devices can help make the adoption of insulin easier for patients.
    Page: 67
    DOI: 10.1097/SMJ.0b013e318182d8a2
    Authors: Hsu, William C. MD

  • Arrow Shaft Injury of the Wrist and Hand: Case Report, Management, and Surgical Technique. -
    Injuries resulting from high- and low-velocity projectiles as well as their initial management are well documented in the literature. Most of the described injuries involve gunshot wounds, some of which involve injuries to the hand and wrist. To our knowledge, there has not been a case described that involves a hollow arrow shaft with fragmentation. This paper presents a case report of such an injury through the wrist and hand. The report illustrates both the unique nature of the injury and describes the techniques and special considerations for surgical management.
    Page: 77
    DOI: 10.1097/SMJ.0b013e3181884500
    Authors: Launikitis, Robert A. MD; Viegas, Steven F. MD

  • Forearm Muscle Metastasis as an Initial Clinical Manifestation of Lung Cancer. -
    A 37-year-old man presented with painful swelling in the left forearm muscle. The biopsy of muscle swelling disclosed the presence of the pulmonary adenocarcinoma. The diagnosis of skeletal muscle metatasis from lung cancer was made. The patient was treated with systemic chemotherapy and radiotherapy. Skeletal muscle metastasis due to primary lung cancer is rare.
    Page: 79
    DOI: 10.1097/SMJ.0b013e31818133db
    Authors: Kaira, Kyoichi MD, PhD; Ishizuka, Tamotsu MD, PhD; Yanagitani, Noriko MD, PhD; Sunaga, Noriaki MD, PhD; Tsuchiya, Takafumi MD, PhD; Hisada, Takeshi MD, PhD; Mori, Masatomo MD, PhD

  • Fulminant Hepatitis Induced by Lamotrigine. -
    This case report describes a patient who developed anticonvulsant hypersensitivity syndrome (AHS) with fulminant hepatic failure two weeks after introduction of lamotrigine. Although hepatoxicity has been previously reported with lamotrigine, very few cases developed fulminant hepatic failure and to our knowledge, this report contains the lowest dosage at presentation and the slowest titration. This suggests that AHS may occur in a purely idiosyncratic manner, independent of dosage and titration.
    Page: 82
    DOI: 10.1097/SMJ.0b013e3181878b95
    Authors: Ouellet, Georges MD; Tremblay, Lydjie BPharm, MSc; Marleau, Denis MD

  • Familial Fahr Disease in a Turkish Family. -
    Fahr syndrome refers to a rare syndrome characterized by symmetrical and bilateral intracranial calcification. A 42-year-old woman presented with Fahr disease, but lacking extrapyramidal symptoms or a metabolic disorder. When screening other family members, we detected Fahr syndrome in two daughters and three brothers, revealing that the disease was an autosomal dominant trait. Fahr disease may be clinically asymptomatic, but have pronounced positive brain imaging findings. Computed tomographic scanning remains the most effective screening tool for adult relatives.
    Page: 85
    DOI: 10.1097/SMJ.0b013e3181833f02
    Authors: Kotan, Dilcan MD; Aygul, Recep MD

  • Cocaine Abuse Complicating Acute Painful Episodes in Sickle Cell Disease. -
    Cocaine use complicating acute painful episodes in patients with sickle cell anemia may be under recognized and may lead to multiorgan dysfunction. Enhanced surveillance is indicated if a history of cocaine abuse is elicited. Early evidence of organ failure should lead to consideration of aggressive interventions such as transfusion therapy. We report clinical outcomes in three patients in which cocaine use preceded a sickle cell pain episode.
    Page: 87
    DOI: 10.1097/SMJ.0b013e318188b2ab
    Authors: Boulmay, Brian MD; Lottenberg, Richard MD

  • A Case of Emphysematous Cystitis in Cystic Fibrosis. -
    Emphysematous cystitis is a rare condition usually seen in patients who are either diabetic or have other immunosuppressive diseases, or have had disruption of the bladder wall due to trauma or surgical instrumentation. We present a case of emphysematous cystitis in a patient with cystic fibrosis without any other underlying immunosuppressive conditions.
    Page: 89
    DOI: 10.1097/SMJ.0b013e318188700c
    Authors: Beri, Abhimanyu MD; Dwamena, Francesca MD

  • Case Report of Mastocytosis in an Adult. -
    A case of adult-onset mastocytosis is presented to illustrate the classification, signs, symptoms, workup, treatment, and prognosis for this unusual condition. Although there is no cure for mastocytosis, symptoms of histamine release can be minimized with oral antihistamines. Ongoing surveillance of organ systems affected remains important. Our patient's mast cell disease predisposed him to bone loss, but there was no evidence of disease beyond the skin. He has done well with continued follow up monitoring his serum tryptase and oral antihistamine treatment.
    Page: 91
    DOI: 10.1097/SMJ.0b013e3181827871
    Authors: Barker, Allison MD; Stewart, Rosalyn W. MD, MS

  • Tuberculous Peritonitis: A Surgical Dilemma. -
    Tuberculous peritonitis can present with a constellation of nonspecific signs and symptoms and may be easily misdiagnosed. This disease process is a rare cause of abdominal pain in the United States, and the diagnosis is entirely dependent upon the level of suspicion by the surgeon. In this case report, we present an example of a typical patient with tuberculous peritonitis, a diagnosis that was made only after laparotomy.
    Page: 94
    DOI: 10.1097/SMJ.0b013e318186e684
    Authors: Khan, Azeem R. MD; Morris, Lee M. MD; Keswani, Sundeep G. MD; Khan, Imtiaz R. BS; Le, Linda MD; Lee, W Chapman MD; Hunt, John P. MD, MPH

  • Anaphylactic-like Reaction to Lugol Solution During Colposcopy. -
    Lugol iodine solution staining of the cervix and vagina during colposcopy examination is known as a Schiller test and is routinely performed by colposcopists. Although iodine anaphylactic-like reactions are described in the literature, they are not reported during Lugol staining of the genital epithelia. This paper focuses on the latter possibility and describes an easy tool to treat it without using drugs.
    Page: 96
    DOI: 10.1097/SMJ.0b013e31818894f4
    Authors: Indraccolo, Ugo MD, PhD; Palombino, Katia MD, PhD; Greco, Pantaleo MD

  • Ruptured Intracranial Dermoid Cyst Presenting With Neuropsychiatric Symptoms: A Case Report. -
    The diagnosis of a ruptured dermoid cyst in a 58-year-old man with chronic psychiatric problems is described. The auditory and visual neuropsychiatric problems resulted from irritation of brain structures by cholesterol particles from the ruptured dermoid cyst. Extirpation of the cyst and it ruptured contents reversed two of the three chronic symptoms and both of the acute symptoms.
    Page: 98
    DOI: 10.1097/SMJ.0b013e318188b290
    Authors: Detweiler, Mark B. MD, MS; David, Efraim MD; Arif, Saira MD

  • Primary Plasma Cell Leukemia Presented as Progressive Paraplegia: A Case Report. -
    A middle-aged man was referred to our center with a history of progressive paraplegia over a period of three weeks. It was associated with multiple soft tissue swelling over the face, left rib and scapular area. He was initially treated in a peripheral hospital for sepsis with underlying cord compression secondary to metastatic disease. Further workup at our center revealed that he had primary plasma cell leukemia with multiple bony lesions and soft tissue infiltrations, complicated by paraplegia secondary to cord compression.
    Page: 101
    DOI: 10.1097/SMJ.0b013e31818018c1
    Authors: Hasmoni, Mohd Hadzri MBBCh, MMed; Wahid, Fadilah Abdul MMed, PhD, FRCP (Edin); Keng, Cheong Soon MRCP (UK), DCP (Lond), FRCP (Glasgow), FRCPA (Aus)

  • Donovanosis Presenting as a Pelvic Mass Mimicking Ovarian Cancer. -
    A 29-year-old female presented with chronic postpartum abdominal pain. CT scan was consistent with ovarian carcinoma, and biopsy yielded macrophages laden with eosinophilic bodies. Cultures, Histoplasma serologies, and Toxoplasma serologies were negative. A diagnosis of pelvic donovanosis was reached; the patient was treated with azithromycin resulting in clinical and radiographic resolution.
    Page: 104
    DOI: 10.1097/SMJ.0b013e31817ff982
    Authors: Barroso, Luis F. MD; Wispelwey, Brian MD

  • Rapunzel and Pregnancy. -
    A 22-year-old woman had been suffering from episodes of epigastric pain and vomiting throughout her pregnancy and puerperium. After diagnosing pancreatitis, we discovered a trichobezoar in her stomach. In an emergent gastrotomy, the patient was found to have a gastric trichobezoar with a long tail extending down to her duodenum. This is one of the very few cases of Rapunzel syndrome complicated by pancreatitis; to our knowledge, it is the first to be reported postpartum.
    Page: 106
    DOI: 10.1097/SMJ.0b013e31818987b9
    Authors: Salem, Mohamed MD, PhD; Fouda, Ragai MD, PhD, MRCP; Fouda, Usama MD, PhD; Maadawy, Mohamed E.L. MD, PhD; Ammar, Hussam MD










  • Spontaneous Recovery from Long-term Phrenic Nerve Palsy. -
    Page: 115
    DOI: 10.1097/SMJ.0b013e318188d0e9
    Authors: Minicucci, Marcos F. MD; Inoue, Roberto M. T. MD; Zornoff, Leonardo A. M. MD; Azevedo, Paula S. MD; Paiva, Sergio A. R. MD; Resende, Luiz A. L. MD; Matsubara, Luiz S. MD; Okoshi, Marina P. MD


  • Medical Webwatch. -
    Page: 118
    DOI: 10.1097/01.smj.0000344151.51280.f5
    Authors: Young, Jim